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In this issue:
The Shape of Things to Come
Science Today: The Many Sides of Cells
Scheduled Computing Outages: When and Why?
Thursday - July 26, 2007 |
The Shape of Things to ComeWhen you pack 16 billion electrons into a space smaller than the head of pin, things get crowded in unpredictable ways. Within a 300-micron-long footprint, the shape of an electron bunch can vary tremendously, and has a big effect on the collision of particles. For example, the electrons—and their negative charge—might congregate at one end of the bunch, or they might scatter evenly throughout, or they might clump together to make randomly placed peaks and valleys. At the proposed International Linear Collider, researchers will need to know the shape of the bunch to calculate how much it was deflected just before striking an oncoming bunch of positrons. Instrumentation to measure bunch shape is being developed by a group from Oxford University and was tested again earlier this month at the test beam in End Station A. Read more... |
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The Many Sides of CellsThe mechanics of a basic cellular process found in most living organisms, including humans, is less of a mystery, thanks to work done in part by Douglas Hattendorf at the Stanford Synchrotron Radiation Laboratory (SSRL). The team of researchers, led by Bill Weis of the Stanford University School of Medicine, solved the structure of a protein that assists in the developmental process of cellular polarization, which gives cells the ability to perform specific biological functions. Polarization occurs in most living cells, and is a feature whereby different sides of individual cells are made up of membranes of differing composition that perform different functions. Epithelial cells in the lining of the gut, for example, possess membranes that absorb nutrients on one side and membranes that connect to other cells on the other side. Special surface proteins determine the composition and function of these differing membranes. The current study sheds light on how these surface proteins find their way to the proper membrane of a cell. Within a cell, pockets called vesicles deliver proteins to the various surface membranes, fusing with the membrane to deliver its cargo. The mechanism behind how vesicles discriminate between the membranes—fusing with some but not with others—has been mostly a mystery. Read more... |
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